A recent review by Dr. Delda Bagis of Turkey demonstrates the relationship between magnesium levels and fibromyalgia, a condition where an individual experiences long term pain in the joints and tendons, which connect bone to muscle. Dr. Bagis conducted her research by comparing blood samples of patients with fibromyalgia symptoms versus patients of the same age without the symptoms. With these blood samples, magnesium levels in both groups were observed. It was found that the patients who had fibromyalgia symptoms had lower magnesium levels.
Dr. Bagis also performed an 8-week study in which three different therapies for fibromyalgia were performed on three groups of 20 patients each. One group was treated with an antidepressant called amitriptyline, the second group was treated with magnesium and the third group with a mixture of both. This study showed that magnesium was essential in reducing tenderness in the muscles, while also playing a role in helping its function. However, the mixture of the antidepressant, amitriptyline, and magnesium was much more effective in treating the symptoms of fibromyalgia.